Mito-TEMPO;MT

Information

CAS No.: 1334850-99-5

Structure Formula:

Molecular Formula: C₂₉H₃₅ClN₂O₂P

Molecular Weight：510.03

Appearance: White to light brown powder

Solubility (at 25°C): 10 mg/mL dissolved in water

Purity: >99%,HPLC

Storage Condition: 

	1 mg	5 mg	10 mg
1 mM	1.9607 mL	9.8033 mL	19.6067 mL
5 mM	0.3921 mL	1.9607 mL	3.9213 mL
10 mM	0.1961 mL	0.9803 mL	1.9607 mL
50 mM	0.0392 mL	0.1961 mL	0.3921 mL

Shipment: 

Description

Scientific research reagent, widely used in molecular biology, pharmacology and other scientific research areas. Strictly prohibited for use in humans.

1. It can eliminate the ROS level in kidney tissue caused by I/R, inhibit the expression of inflammatory factors, and simultaneously improve the abnormal structure and function of mitochondria, protecting the renal function of I/R.
2. It also has a significant improvement effect on the impairment of cardiac function caused by type II diabetes. It can inhibit the level of mitochondrial ROS, protect the structure and function of mitochondria, while also inhibiting the expression of myocardial hypertrophy factors, improving myocardial hypertrophy and protecting cardiac function.
3. It can significantly reduce the accumulation of mitochondrial ROS in adipose stem cells in a diabetic environment and alleviate the oxidative stress injury caused by it, such as restoring the viability of diabetic adipose stem cells, improving the differentiation ability of adipocytes and osteoblasts, and restoring cell migration ability.
4. It can improve H9c2 cell H/R injury by inhibiting mitochondrial oxidative stress and apoptotic responses.
5. It can inhibit oxidative stress injury in multiple tissue cells, and melatonin, curcumin, and DNA methyltransferase inhibitor 5-azacitidine (5-Azacitidine, 5AZA) can inhibit the level of oxidative stress in ADSCs and enhance cell viability.

Usage Statement

Research Use Only (RUO)