Information
Chemical Name: 3.6′-bis(acetyloxy)-3-oxo-2.5-dioxo-1-pyrrolidinyl ester-spirolisobenzofuran-1(3H).9′-[9H]xanthene]-ar-carboxylic acid
CAS No.: 150347-59-4
Molecular Structure: 
Molecular Formula: C29H19NO11
Molecular Weight: 557.47
Purity: ≥95%
Appearance: Yellow powder
Storage Condition: Store at -20°C, Protect from light.
Shipment:
Description
CFDA-SE is a stable, cell-permeable dye that consists of a fluorescein molecule containing two acetate moieties and a succinimidyl ester (SE) functional group. Upon diffusion into the intracellular environment the acetate groups are cleaved by cellular esterases leaving CFSE, which is fluorescent and not cell permeable. CFSE covalently couples to intracellular molecules via its succinimidyl group and can be retained in cells for at least eight weeks. CFDA-SE is often used to assay cell proliferation as it is partitioned with high fidelity between daughter cells for up to eight generational divisions. CFSE, the cleavage product of CFDA-SE, displays excitation/emission maxima of 491/518 nm, respectively.
Usage Statement
Research Use Only (RUO)
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